This seminar will provide an overview over the location, tributary regions and imaging features of normal thoracic and abdominal lymph nodes in dogs and cats as well as imaging features seen with regional and systemic inflammatory diseases, and primary, disseminated and metastatic neoplasia. The focus of the presentation will be on CT, but ultrasound and MRI images may be included. Participants will learn about the yield and limitations of diagnostic imaging in lymph node staging of small animal oncology patients.