Aging Haemorrhage on MRI

by Swan Specchi, DVM, PhD, DACVR | 2017-04-06

hyperacute: intracellular oxyhaemoglobin

  • isointense on T1
  • isointense to hyperintense on T2

acute (1 to 2 days)

  • intracellular deoxyhaemoglobin
  • T2 signal intensity drops (T2 shortening)
  • T1 remains intermediate-to-low

early subacute (2 to 7 days)

  • intracellular methaemoglobin
  • T1 signal gradually increases (T1 shortening) to become hyperintense

late subacute (7 to 14-28 days)

  • extracellular methaemoglobin: over the next few weeks, as cells break down, extracellular methaemoglobin leads to an increase in T2 signal

chronic (>14-28 days)

  • periphery
    • intracellular haemosiderin
    • low on both T1 and T2
  • center
    • extracellular hemichromes
    • isointense on T1, hyperintense on T2